撰写这篇国际专家共识的初衷源于一次肺癌会议上的深刻讨论，我们意识到尽管BRAF突变在多种肿瘤中普遍存在，但其检测与治疗策略却缺乏统一的 ...

We played a major role in characterising the BRAF gene and its role in cancer, increasing our understanding of malignant melanoma. Our work on the gene and the structure of the BRAF protein ...

Oncogenic activation usually results from point mutation rather than gene rearrangement. The most common BRAF mutation is the T1796A point mutation, resulting in a glutamic acid (E) to valine (V ...

A new clinical trial highlights that spotting a genetic subtype of these ATC tumors can be key to designing treatment that ...

A new clinical trial highlights that spotting a genetic subtype of these ATC tumors can be key to designing treatment that greatly extends survival ATC patients with BRAF gene mutations lived a ...

BRAF V600E mutations are seen in around 20 different ... The findings reinforce the importance of genetic testing for cancers to enable the use of targeted treatment, according to ROAR's lead ...

Caris Life Sciences has obtained an FDA approval for its MI Cancer Seek tumor profiling assay, unlocking its use as a ...

HCL uniformly harbors a BRAF mutation that is not present in other B-cell malignancies. Hairy cell leukemia (HCL) is an indolent B-cell lymphoproliferative disorder that responds to several highly ...