发育和衰老贯穿人类一生,伴随着免疫系统的逐渐成熟和不可避免的退化。出生后,免疫系统逐渐成熟,能够更好地抵御外来病原体。相反,免疫老化导致感染、心血管疾病和癌症的发病率更高。此外,最近有报道称,老化的免疫细胞会导致心脏和肝脏等实体器官的老化,这可能是全 ...
近日,上海交通大学医学院附属仁济医院心内科卜军课题组在《Nature Immunology》发表了研究论文“Integrating single-cell RNA and T cell/B cell receptor sequencing with mass cytometry reveals dynamic trajectories of human peripheral immune ...
The pre-B-cell receptor (pre-BCR), which comprises two Igμ chains and two germline-encoded surrogate light chains (SLC) that are associated with the signalling subunits Igα and Igβ, is formed ...
Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic ...
Pfizer’s Takeda-partnered blood cancer drug Adcetris (brentuximab vedotin) has been approved by the US Food and Drug ...
The FDA has approved Adcetris (brentuximab vedotin) for use in combination with lenalidomide and rituximab to treat patients with relapsed/refractory LBCL after 2 or more lines of systemic therapy who ...