发育和衰老贯穿人类一生，伴随着免疫系统的逐渐成熟和不可避免的退化。出生后，免疫系统逐渐成熟，能够更好地抵御外来病原体。相反，免疫老化导致感染、心血管疾病和癌症的发病率更高。此外，最近有报道称，老化的免疫细胞会导致心脏和肝脏等实体器官的老化，这可能是全 ...

该研究首次描绘了人类外周 免疫 ...

近日，上海交通大学医学院附属仁济医院心内科卜军课题组在《Nature Immunology》发表了研究论文“Integrating single-cell RNA and T cell/B cell receptor sequencing with mass cytometry reveals dynamic trajectories of human peripheral immune ...

A GROUNDBREAKING study has revealed how the human immune system evolves across the lifespan, uncovering age-specific changes ...

We use two models of human pre-B-ALL to examine EphA3 function, demonstrating effects on pre-B-cell receptor signaling. In therapeutic targeting studies, we demonstrated antitumor effects of the ...

Chronic lymphocytic leukemia (CLL) is a B-cell malignancy, with disease progression ranging from slow and indolent to ...

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic ...

Pfizer’s Takeda-partnered blood cancer drug Adcetris (brentuximab vedotin) has been approved by the US Food and Drug ...

a 3-year single center retrospective study of CD19-directed chimeric antigen receptor T-cell therapy for relapsed and refractory B-cell lymphomas, Haematologica (2024). DOI: 10.3324/haematol.