In 2000, it was suggested to me that “Autophagy will be the wave of the future; it will become the new apoptosis.” Few people would have agreed at the time, but this statement turned out to be ...

Autophagy has been recently shown to be an important component of the innate immune response by degrading foreign microbial invaders. The upstream signaling pathways leading to activation of autophagy ...

Autophagy is a natural regeneration process that occurs at a cellular level in the body, reducing the likelihood of contracting some diseases as well as prolonging lifespan. In 2016, Japanese ...

AMPK signaling promotes an increase in cell stiffness that drives entotic ingestion into winners (Fig. 2). AMPK signaling is also well known to activate the nutrient recycling mechanism autophagy. We ...

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered in diseases, including neurodegenerative disease. To this end ...

Diabetes drug development gets an advance in study that shows Inceptor binds excess insulin within the beta cell and directs it towards degradation.

We have observed implantation defects and thus, reduced fecundity in conditional knockout mice models of the autophagy-related proteins in the reproductive tract. In the absence of these proteins, we ...

Damaged or superfluous proteins and other components inside a cell are broken down in a process called autophagy. Aging research has established that autophagy pathways become less active with age ...

Detailed price information for Immunoprecise Antibodies Ltd (IPA-Q) from The Globe and Mail including charting and trades.