What do cells do when they are “hungry”? Eukaryotic cells cope with starving conditions by eating their own components, a process called autophagy. Aa Aa Aa Normally, when you are hungry you ...

Finally, metabolic flux analysis using 14 C- or 13 C glucose in red ripe fruits showed decreasing rate of protein synthesis alongside the 14 CO 2 evolution on lack of autophagy in Arabidopsis. However ...

Autophagy is a natural regeneration process that occurs at a cellular level in the body, reducing the likelihood of contracting some diseases as well as prolonging lifespan. In 2016, Japanese ...

More information: Mingang Hao et al, In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux, Cell Reports ...

Damaged or superfluous proteins and other components inside a cell are broken down in a process called autophagy. Aging research has established that autophagy pathways become less active with age ...

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered ... quantitative proteomics workflows to examine how flux in ...