Novel drugs for atherosclerosis have taken a hard hit in the past year, making it unlikely that any will make it to market this decade. But lessons learned from these failures might help the ...

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

Objectives To examine the associations between physical fitness in male adolescents and coronary and carotid atherosclerosis in middle age. Methods This population-based cohort study linked physical ...

Our opinion: At this point, we do not recommend changing exercise habits (including intensity) in asymptomatic athletes to reduce progression of coronary atherosclerosis, since current cross-sectional ...

Heart disease remains the leading cause of death in the United States, even with decades of effort focused on controlling ...

Subclinical atherosclerosis and mortality, Journal of the American College of Cardiology (2024). DOI: 10.1016/j.jacc.2024.06.045 Provided by Centro Nacional de Investigaciones Cardiovasculares ...

Artery hardening, also known as atherosclerosis, is a condition that affects millions of people worldwide. It happens when ...

finding that reducing SPT activity did decrease trans fat-induced atherosclerosis. According to Metallo, these findings make this sphingolipid synthesis pathway through SPT a critical target for ...