Atherosclerosis and related cardiovascular diseases represent one of the greatest threats to human health worldwide. Despite important progress in prevention and treatment, these conditions still ...

Novel drugs for atherosclerosis have taken a hard hit in the past year, making it unlikely that any will make it to market this decade. But lessons learned from these failures might help the ...

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

Heart disease remains the leading cause of death in the United States, even with decades of effort focused on controlling ...

Objectives To examine the associations between physical fitness in male adolescents and coronary and carotid atherosclerosis in middle age. Methods This population-based cohort study linked physical ...

This article was reviewed by Craig Primack, MD, FACP, FAAP, FOMA. Atherosclerosis happens when a fatty substance called plaque builds up inside your arteries. There are typically few noticeable ...

Atherosclerosis is the main cause of cardiovascular ... and genetic data improves risk stratification, European Heart Journal (2024). DOI: 10.1093/eurheartj/ehae768 ...

In a new study, published in the journal Cell Reports ... "We have already seen its effectiveness in multiple models of atherosclerosis," Maiseyeu said. "We are optimistic that this will result ...

finding that reducing SPT activity did decrease trans fat-induced atherosclerosis. According to Metallo, these findings make this sphingolipid synthesis pathway through SPT a critical target for ...