Key experiments in the early 1990s (surely a golden period in apoptosis research) helped us understand the mechanisms by which these genes control apoptosis. The structure of CD95 suggested that ...

Whether cells in the human body survive or die under stress depends, among other things, on their mitochondria.

Scientists at the Faculty of Medicine at the University of Freiburg have now shown that a sudden stop in energy production in ...

Both diseases center on one of the key mechanisms used to keep the rest of the body in check. Apoptosis, or programmed cell death, is a crucial tool immune cells use to remove malfunctioning or ...

Researchers discover how mitochondria not only produce energy but also influence inflammation.

If the ATP in the mitochondria drops sharply, a protein important for apoptosis, known as cytochrome c, remains trapped in the mitochondria and the cell does not die, even if it receives the signal to ...