Rubius Therapeutics is a biopharmaceutical company based in Cambridge, Massachusetts, USA, that is developing allogeneic cell therapies based on biologically engineered red blood cells (RBCs).

T cells, move over. B cells are now reported, in a recent paper in Nature, to have their own immunological synapses with APCs. Only this time the antigen is whole and B cells don't keep it to ...

An army of defensive cells protects the body against invasion by foreign substances: the antigens. The specialized functions of these various "inflammatory" cells are now being clarified ...

The story begins in 1972 when doctors examining a pregnant woman's blood sample noticed something peculiar. Her red blood ...

Initially designed for hematological malignancies, CAR-T therapy is now being expanded to target solid tumors using specialized CAR-T cells that attack specific antigens. Ongoing clinical trials are ...

In this event, the plasma, which is usually group O transfused to A, B or AB recipients, may contain sufficient potent antibodies directed against A or B antigens on the recipient's red cells to ...

was used to investigate immune cell induction in PPs in response to dietary antigens. Peyer's patches as immune hubs: Peyer’s patches in the small intestine are crucial for inducing T-cells in ...

Blood types describe the rich variety of chemicals displayed on the surface of our red blood cells. Among the most familiar ...

Ohno and his team have previously reported that food antigens activate immune cells in the small intestines, but not the large intestines. At the same time, some immune cells activated by gut ...

In living things, diffusion allows substances to move in and out of cells. It's how red blood cells distribute oxygen through the body. When empty blood cells enter the lungs, which have an ...

In new research done on mice, scientists point the finger at a small subset of blood stem cells, which make an outsized contribution to maintaining either a ... Oct. 24, 2024 — Researchers ...

This valuable study reports on a novel role of PD-1 in early T cell differentiation, showing that PD-1 stimulation impairs Th2 differentiation more effectively than that of Th1, with implications for ...