The life expectancy of people with Angelman syndrome is normal, but individuals with the condition will require life-long ...

People who have the syndrome usually have a normal life expectancy. Symptoms of Angelman syndrome can sometimes be confused with other disorders that also cause developmental delays, such as ...

The NIH estimates that 1 in 12,000 to 20,000 individuals have Angelman syndrome, and the life expectancy of people with Angelman syndrome "appears to be nearly normal." The father-son duo have ...

Angelman syndrome is caused by a large deletion of the region of the maternal chromosome that contains UBE3A, or by a DNA sequence change (mutation) in the UBE3A gene inherited from the mother.

We each get two copies of every gene - one copy from each of our parents. But what happens when one of these genes has been "turned off", or imprinted, and the remaining gene is defective?