Current approaches targeting androgen receptor (AR) signaling, such as taxanes and newer agents, show limited success. Cisplatin, a widely used anticancer drug, has been used in combination ...

A protein called the androgen receptor normally functions to guide the development of the prostate—signaling the cells to stop growing, act as normal prostate cells and maintain a healthy state.

Scientists unveil the androgen clock, a precise epigenetic tool to measure long-term androgen exposure and its role in aging ...

Discover recent research that has unveiled the crucial role of Androgen Response Elements in governing androgen receptors ...

The understanding of the biology of CRPC and the evidence that CRPC still remains driven by androgen receptor signaling led to the discovery of new therapeutic targets. In the last few years ...

The key to this resistance may lie in expression of the androgen receptor itself. Most patients with metastatic prostate cancer receive drugs that block production of androgen, which promotes ...

Athletes and fitness enthusiasts are always looking for advanced solutions to improve performance, recovery, and muscle growth.

While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-resistant ...