Currently, the only exception to our feedback view of irreversible transitions in the cell cycle is the separation of sister chromatids at anaphase, which is accomplished by the proteolysis of ...

The membrane around the nucleus disappears. Metaphase Chromosomes and their copies line up in the middle of the cell. Anaphase Chromosomes and their copies are pulled to different ends of the cell.

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.