The allele frequency represents the incidence of a gene variant in a population. Alleles are variant forms of a gene that are located at the same position, or genetic locus, on a chromosome.

A combination of two “active” therapies may help slow cognitive decline in older adults, especially those with a type of ...

Penetrance is a measure of the proportion of individuals in a population carrying a particular allele that expresses the related phenotype. In contrast to multifactorial diseases, Mendelian ...

The HLA-DRB1*01:03 allele explained this association overall (OR 3.32, 95% CI 2.25-4.89, P=1.45 × 10-9) and in the two ...

ASHG welcomed eight 2024–2026 Human Genetics Scholars who are recognized for their accomplishments and commitment to fostering DEI in human genetics and genomics.

DRB1*01:03 genetic variant is associated with severe ulcerative colitis, significantly raising the risk of major surgeries ...

A spotless cheetah, a sight unseen for almost a century, has been photographed in Kenya's Athi Kapiti Conservancy. This rare ...

The Alzheimer's disease drug Kisunla will face major reimbursement challenges in the U.K. after the cost-effectiveness ...

The study is evaluating AJ1-11095, a novel agent for the treatment of myelofibrosis that did not respond to or relapsed ...

The study identifies links between gut microbiota, genetic variants in IBD, and mental health disorders, offering insights ...

Among patients with polycythemia vera, the treatment pairing of Jakafi and Pegasys shows benefits with acceptable toxicity, ...

The association between the HLA-DRB1*01:03 allele and ulcerative colitis has been noted previously, but there is a clinical need for biomarkers that could identify which patients are more likely ...