Compared with placebo, sodium zirconium cyclosilicate was associated with less need to lower or discontinue spironolactone.

Potassium and renal function must be routinely assessed to minimize the risk of life-threatening hyperkalemia. This review discusses the role of aldosterone antagonists in the treatment of heart ...

Aldosterone is a hormone produced in the adrenal gland. This steroid molecule, derived from cholesterol, promotes retention of sodium and water and lowers the levels of potassium in the blood ...

This process is influenced by hormones such as aldosterone, which increases potassium excretion, and is also affected by the body’s acid-base balance. Finally, any excess potassium that is not ...

Aldosterone is a steroid hormone that plays a critical role in the homeostasis of sodium, potassium and volume. Aldosterone is secreted primarily by cells of the zona glomerulosa in the adrenal ...

Contraindicated in patients with high potassium levels in the blood, aluminum toxicity, heart failure or injury, or severe kidney problems, who are taking aldosterone blocker and hypersensitivity.

Nursing mothers. Avoid concomitant potassium-sparing diuretics. Monitor for hyperkalemia with drugs that inhibit the renin-angiotensin-aldosterone sytem (eg, ACE inhibitors, ARBs, spironolactone ...

increases in aldosterone secretion, increases in urinary potassium loss, and decreases in serum potassium. Fetal toxicity may develop; discontinue if pregnancy is detected. Correct salt/volume ...