Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

"We identified 13 clusters, some of which expressed genes associated with hormone production, especially CYP11B2, which encodes an enzyme that produces aldosterone." Simulated analysis of how ...

In the presence of neurohormonal activation, angiotensin II causes aldosterone production in the adrenal cortex, which acts on the cortical collecting tubules to conserve sodium. Aldosterone may ...

Baxdrostat is a drug that reduces aldosterone levels in the body to treat high blood pressure and other conditions. It's an ...

PET/CT imaging with gallium-68 (Ga-68) pentixafor can effectively guide surgery for patients with primary aldosteronism, ...

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally, when ...

Splanchnic vasodilation increases the production of vasodilators (nitric ... including the renin–angiotensin–aldosterone system, sympathetic nervous system, and arginine vasopressin, are ...