Potassium and renal function must be routinely assessed to minimize the risk of life-threatening hyperkalemia. This review discusses the role of aldosterone antagonists in the treatment of heart ...

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally ...

Aldosterone also promotes potassium and magnesium depletion, which is potentially proarrhythmic. Aldosterone was originally thought to be blocked by ACE inhibitors. However, it is now known that ...

Primary aldosteronism treatment response was associated with higher plasma renin activity and serum potassium levels and lower aldosterone.