Summary: Heart failure ... angiotensin–aldosterone system, which compensates for the hypoperfusion. However, this contributes to the pathology of the disease by, among other actions, increasing ...

When this occurs, your blood vessels narrow, and your heart beats faster and with ... by blocking a chemical called aldosterone. This action reduces the amount of fluid your body retains, which ...

Although diuretics do not directly treat the pathologic changes that occur with heart failure ... through a different mechanism of action. In recent years, aldosterone antagonists have been ...

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone ... in systolic heart failure with recent or current New ...