and the common low-affinity p75 neurotrophin receptor as well as the activation of downstream PI3K/Akt and MAPK/ERK signaling pathways. However, their precursor proteins (pro-BDNF and pro-NGF ...

Here, Alison Halliday shares the story of how our researchers revealed the 3D structure of the key cancer protein AKT, catalysing the discovery and development of at least 12 drugs now in clinical ...

This project is an integral part of RUSI’s work on counter proliferation financing, which focuses on supporting governments and private sector industry globally to counter proliferation financing.

Access to the financial system and financial services is central to proliferation efforts, and disrupting this financing is key to countering the spread of WMDs. Since 2015 RUSI has produced ...

Explore Foreign Affairs’ coverage of nuclear weapons and nuclear proliferation, including North Korea’s nuclear program, the possibility of a nuclear escalation with Russia, and the status of the Iran ...

Then, IL-2 signaling is transduced through three distinct pathways: JAK-STAT, MAPK/ERK and PI3K/Akt/mTOR ... IL-2 protein also enables the proliferation of mitogen-activated T cells and NK ...

From militancy in the Niger Delta to insurgency in the North-East and banditry across the North-West, the proliferation of illegal arms exacerbates Nigeria’s security woes. Given the critical ...

Proliferation index is an important prognostic factor in breast cancer. The Ki-67 protein is expressed in all phases of the cell cycle except G0 and serves as a good marker for proliferation. Studies ...

However, insulin, the most potent anabolic hormone in the body, exerts a multitude of effects on lipid and protein metabolism, ion and amino acid transport, cell cycle and proliferation ...

决定依据《国家自然科学基金项目科研不端行为调查处理办法》第五十条第一项、第四项和第四十四条第四项，取消全成国家自然科学基金项目评审专家资格3年（2024年4月9日至2027年4月8日），取消全成国家自然科学基金项目申请和参与申请资格2年（2024年4月9日至2026年4月8日），给予全成通报批评。