In the case of GSK’s recombinant herpes zoster vaccine, a proprietary Adjuvant System plays a key role in its high efficacy, by helping to boost the immune response. This adjuvant is part of an ...
GSK announced on Friday that the US Food and Drug Administration (FDA) has accepted its regulatory application for a ...
Of these adjuvants, the ones that contain aluminium ... which allowed prolonged and effective stimulation of the immune system, an effect referred to as the 'depot effect'. For approximately ...
Effective adjuvant systems require synergy between immunostimulants and delivery system. Immunomodulator adjuvants that can enhance cytotoxic T lymphocyte or Th1/Th2 responses, and/or affect ...
Lipopolysaccharide functions as a vaccine adjuvant but is considered too toxic for clinical use. The major structural element responsible for its toxicity and adjuvant effect is lipid A.