Nature6y
Three is the magic number in gene therapy production
The combined activity of the adenovirus-derived genes on the helper plasmid with the rAAV genes on the second plasmid proved sufficient to generate functional rAAV particles containing the ...
Baylor College of Medicine4y
Gene Vector Core
The Gene Vector Core was awarded the Blue Flame Award. The award is given to scientists who have at least one plasmid deposited that has been distributed at least 100 times. The Gene Vector Core was ...
Baylor College of Medicine4y
Adenovirus Vectors
This cassette is then transferred to the adenovirus vector plasmid (pAdeno X, Clontech Laboratories or pAd5F35, The Journal of Gene Medicine Volume 6, Issue 6 , Pages 631 - 641). The adenovirus vector ...
Nature6y
A helping hand for gene therapy production
A 1984 paper by Paul Hermonat and Nicholas Muzyczka offered the first demonstration that AAV might provide a safe and effective vehicle for transgene delivery, with helper adenovirus infection ...