CRISPR-Cas10 protects bacteria by releasing toxins into virus-infected cells, stopping the infection from spreading.

CRISPR-Cas9 has long been likened to a kind of genetic scissors, thanks to its ability to snip out any desired section of DNA ...

Vertex may have pivoted away from the space, but candidates in development by Arrowhead/Takeda, Wave, Korro and others could ...

ShapeTX uses a guide RNA that can recruit the cell’s own adenosine deaminase acting on RNA (ADAR) enzymes to edit a precise location on a target RNA. ADARs can correct guanine-to-adenine (G-to-A ...

Early data from Wave Life Sciences suggests how editing RNA may yield viable medicines. Large and small drugmakers say such ...

In these studies, the systemic administration of erdosteine reduced the tissue and/or plasma concentration of xanthine oxidase and adenosine deaminase, enzymes that amplify a free radical ...

We have been exploring the potential of the neuromodulator, adenosine, to reduce excessive dopamine signaling that contributes to the development and persistence of psychostimulant abuse. Dopamine’s ...

ATP works by losing the endmost phosphate group when instructed to do so by an enzyme. This reaction releases a lot of energy, which the organism can then use to build proteins, contact muscles, etc.

How does your body speed up these important reactions? The answer is enzymes. Enzymes in our bodies are catalysts that speed up reactions by helping to lower the activation energy needed to start a ...

A popular experiment that's recommended to demonstrate the functionality of enzymes is chewing a piece of bread for a moment, then paying attention to when it turns from a starchy flavor to begin ...

Nanomedicine. 2012;7(8):1253-1271. Although passive targeting approaches form the basis of clinical therapy, they suffer from several limitations. Ubiquitously targeting cells within a tumor is ...