Chromosome abnormality is the condition in a cell or organism where the number of chromosomes or the structure of any chromosome differs from the normal karyotype. When the variant genotype is not ...

Taken together, these banding techniques offer clinical cytogeneticists an arsenal of staining methods for diagnosing chromosomal abnormalities in patients. In order to maximize the diagnostic ...

A novel molecular tool developed by a Lehigh University professor of biological sciences is enabling scientists to precisely ...

Such research has the potential to correct chromosome abnormalities that lead to birth defects, intellectual disabilities and growth problems. Wynshaw-Boris and his team studied patients who had ...

“The most common cause is the abnormalities of the chromosomes, which lead to miscarriages usually within 12 weeks of pregnancy,” said Dr Salima Wani, consultant gynaecologist and obstetrician ...

When chromosomes don't pair up side-by-side precisely, failed separation can result, leading to abnormal chromosome numbers in an egg and potential infertility, pregnancy loss or conditions such ...

Chromosomal abnormalities can include two basic categories: numerical or structural. A structural abnormality can include an alteration to the structure of the chromosome, as the name suggests.

There are 2 basic types of chromosomal imbalance: aberrations in chromosome numbers (numerical abnormalities) and defects in chromosome structure (structural anomalies). These can be diagnosed by ...

2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that the marker is lacking ...