Chromosome abnormality is the condition in a cell or organism where the number of chromosomes or the structure of any chromosome differs from the normal karyotype. When the variant genotype is not ...

Taken together, these banding techniques offer clinical cytogeneticists an arsenal of staining methods for diagnosing chromosomal abnormalities in patients. In order to maximize the diagnostic ...

A woman got routine bloodwork during her second pregnancy and was shocked when the test results came back: It suggested her ...

The biological factory that produces reproductive cells has a robust quality control system to identify and eliminate eggs ...

These cells are known as aneuploid cells, and have an abnormal number of chromosomes. They're common in invasive breast ...

The study's findings have implications for early detection and prevention of breast cancer, suggesting that chromosomal ...

A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities ...

Apart from translocations, the changes in chromosome structure are: Duplications. This happens when there is abnormal copying of part or whole of the genetic material of a chromosome. The cell ...

The genes present on the duplicate chromosome are "read" more frequently overall, so their products—proteins—build up to ...

Mosaicism has been linked to various pathologies including Turner syndrome, which is a chromosomal abnormality, and to various forms of cancer. Potential symptoms can also include cancer ...

2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that the marker is lacking ...