Neuroscientists say they have determined how a brain cell surface molecule shapes the way certain neurons behave.

Explore how CP-AMPA receptors regulate neuron selectivity and impact brain conditions like autism and epilepsy in a new Johns ...

Neuroscientists have discovered how the CP-AMPA receptor in brain cells influences neuron selectivity in response to sensory ...

R esearchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, used high-speed atomic force microscopy ...

Inhibition of AMPA receptor endocytosis could help treat addiction to heroin. Van den Oever et al. have used a rat model to demonstrate that the link between re-exposure to preconditioned stimuli ...

Some of those most differentially methylated play important roles in glutamatergic signaling, such as Grin2b and Gria2, which encode subunits 2b and 2 of the NMDA receptor and AMPA receptors, ...

In this study the authors showed that GSK3β is present in dendritic spines and is associated with AMPA (α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid) receptors, the trafficking of which ...

重点推荐扫码下载《动物行为实验手册》pdf我们的大脑中包含兴奋性的神经元和抑制性的中间神经元，许多研究表明，皮层的兴奋性神经元能够对特定的外界刺激进行选择性的编码（例如视觉皮层兴奋性神经元响应不同角度的光栅刺激等），但是抑制性的中间神经元，例如PV神 ...

Possibly supporting this interpretation: the composition of receptor subunits within both NMDA and AMPA receptors was skewed in the LOAD2 mice. Their NMDA receptors contained more NR2B subunit, which ...

Additional novel mechanisms are being studied or have been recently approved, spanning NMDA and AMPA receptor modulators, dual orexin receptor antagonists, 5HT2a receptor antagonists, GABA A ...

The neurotransmitter dopamine helps form long-term memories by increasing the production of proteins through a unique signaling pathway.

Perampanel is a non-competitive antagonist of the ionotropic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor on post-synaptic neurons. Glutamate is the primary ...