2). The company is proceeding with additional capsid campaigns derived from AAV9, AAV5, and other AAV serotypes to identify novel capsids optimized for AAV delivery for specific therapeutic ...

In fact, a variety of AAV serotypes can be used to achieve different tissue tropism, efficacy and drug delivery effects. Due to their diversity, and the need to remove process-related impurities, the ...

“The tropism of natural AAV serotypes is limited,” he says. “They also tend to infect the liver, which can cause severe side effects in some cases.” Improving AAV tropism could offer ...

AMSBIO have packaged these indicators into the most commonly used AAV serotypes (AAV8 and AAV9). AMSBIO also has the experience and expertise to assist research groups that require a different ...

Adeno-associated virus (AAV) vectors have emerged as a pivotal tool in gene therapy, offering a promising delivery system in treating genetic disorders. As AAV vector applications in gene therapy ...

the addition of the new kits for serotypes AAV2 and AAV8 extends the range’s suitability to approximately 70% of the AAV gene therapy market, with AAV2 being the most prevalent serotype in clinical ...