The efficacy and safety of and key clinical considerations for using U-500 insulin human regular ... × 0.2 = unit markings in a U-100 insulin syringe, dose (actual units) × 0.002 = volume ...

Because a dedicated U-500 insulin syringe or pen device is not available, patients have to be clearly instructed by their prescriber on how to use either U-100 insulin or tuberculin syringes to ...