5-lipoxygenase (5-LO) — an enzyme that is crucial for the synthesis of a class of pro-inflammatory lipids known as leukotrienes — has been identified as a potential therapeutic target for ...
5-LO is specifically responsible for leukotriene (LT) formation and often associated with neutrophil chemotaxis (Fig. 1). Neutrophil counts were performed on paraffin embedded, anti-neutrophil ...
GSH的生成依赖于半胱氨酸的供应，而半胱氨酸通过细胞膜上的转运体导入细胞，一旦GSH耗尽，GPx4无法正常发挥功能，细胞将变得易于发生铁死亡【5】。线粒体是活性氧（ROS）生成的主要场所，高水平的ROS会导致细胞的氧化性死亡，而抑制线粒体ROS特别是脂质ROS ...
or 5-lipoxygenase inhibitors at baseline. Flovent HFA at dosages of 220 and 440 mcg twice daily was evaluated over a 26-week treatment period in 89 and 93 subjects, respectively. Trial 5 enrolled ...
Annu Rev Cell Dev Biol. 2021 Oct 6;37:233-256. PMID: 34213953. PMC34213953 Katikaneni A, Jelcic M, Gerlach GF, Ma Y, Overholtzer M, Niethammer P. Author Correction: Lipid peroxidation regulates ...
Quassia amara extract showed improvement in most participants, significantly affecting telangiectasia. Feverfew inhibited 5-lipoxygenase and cyclooxygenase, resulting in a reduction in platelet ...
(2020) Lipid peroxidation regulates long-range wound detection through 5-lipoxygenase in zebrafish. Nat Cell Biol. Sep 22;(9):1049-1055. Lee C, Lamech L, Johns E, Overholtzer M. (2020) Selective ...
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Live commentary of South Africa v New Zealand the ICC Women's T20 World Cup final.
K. Suresh Babu, MD, DNB; and Sundeep S. Salvi, MD, DNB, PhD, From the Department of Respiratory Cell and Molecular Biology, University of Southampton, Southampton ...
NewsChannel 5+ (or “The Plus” as we call it) has been connecting our community for almost 30 years. We produce live, local programming where viewers are invited to ask questions, as well as ...
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