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It is very difficult to determine the duration of action of 5-HT 3-receptor antagonists at vagal afferent neuronal receptors. A surrogate test that may have clinical relevance is the duration of ...

The results of these three large trials established palonosetron as an active and well-tolerated new 5-HT3 antagonist. In the setting of moderately emetogenic chemotherapy, there is a suggestion ...

Ondansetron (as HCl dihydrate) 4mg/5mL; strawberry flavor. Ondansetron is a selective 5-HT3 receptor antagonist. Serotonin receptors of the 5-HT3 type are present both peripherally on vagal nerve ...