Meaning that a 12-pound brisket will need between 6 and 12 hours on the smoker plus an additional 1 to 3 hours of prep time for brining. After that, it'll still need to sit for at least an hour ...

While it ultimately depends on method of cooking as directed in the recipe, it generally takes about 1 hour per pound of uncooked brisket if smoking at a very low temperature like 250°F ...